Compositions and methods of cleaning polyvinyl pyrrolidone-based hemodialysis filtration membrane assemblies
AssigneeNovaflux Inc.
InventorsMohamed Emam Labib, Yacoob Tabani
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AssigneeNovaflux Inc.
InventorsMohamed Emam Labib, Yacoob Tabani
Estimating the term…
A method and a composition of cleaning and reprocessing a hemodialysis filtration membrane assembly that employs polyvinylpyrrolidone-containing membranes, the method comprising the step of treating the assembly with an aqueous mixture or a gas-liquid mixture comprising an inorganic base and from 100 to 1,000 ppm of a hypochlorite salt, wherein the mixture has a pH between about 12.0 and about 12.5, an oxidation reduction potential of less than 0.5 volts, a temperature of 40° to 55° C. and wherein the mole % of hypochlorous acid, HOCl, relative to the sum of hypochlorous acid plus hypochlorite anion, —OCl, is less than 0.004%.
A method of cleaning a hemodialysis membrane assembly and removing protein from the pore structure of the membrane, the hemodialysis membrane assembly comprising inlet and outlet ports for a blood compartment, and inlet and outlet ports for a dialysate compartment wherein, in use, blood flows through a plurality of semi-permeable membrane hollow fibers of the blood compartment, each hollow fiber consisting of a lumen and a porous membrane wall, the method comprising:
A surfactant free cleaning composition concentrate effective for cleaning polyvinylpyrrolidone (PVP)-containing dialysis membrane assemblies and removing protein from the pore structure of the membrane without erosion of PVP, said cleaning composition comprising:
Dependencies are inferred from the claim text.