Metered liquid droplet inhaler

A metered liquid droplet inhaling device for delivering medicament, comprising:

• a generally elongated tubular chassis having opposite distal and proximal ends;
• a medicament container holder releasably connected to the chassis by a first engagement device;
• a medicament container arranged inside the medicament container holder, wherein the container comprises a tubular form having at least one chamber configured for containing a composition, a proximal opening for allowing the composition to be expelled therefrom, and at least one axially movable piston, the at least one axially movable piston being coaxially movable along a long axis of the generally elongated tubular chassis;
• a dose knob accessible outside the distal end of the chassis for setting a dose to be expelled by accumulating a rotational force;
• a power supply mechanism configured for converting the rotational force into an axial force to be applied to the piston and thereby to create a pressure inside the medicament container;
• an activation device in mechanical connection to the power supply mechanism;
• a mouth piece mechanically connected to the proximal part of the container holder, wherein the mouth piece comprises a mouth engaging area and an air opening;
• a droplet generator having a plurality of through passing orifices and arranged in the mouth piece, wherein the orifices are in fluid communication with the proximal opening of the container and with the mouth piece;
• and
• a rotating damping member mechanically connected to the power supply mechanism for damping an initial pressure peak inside the medicament container and having a distal part that rotates about an axis that is coaxial with long axis of the generally elongated tubular chassis, and the distal part being separated from the piston on the long axis;
• wherein the power supply mechanism comprises:
• a threaded plunger rod having opposite distal and proximal ends, and having its proximal end in contact with the piston of the medicament container;
• a drive nut threadedly connected to the threaded plunger rod;
• an arbor rotatably connected to the dose knob accessible outside the distal end of the chassis, the arbor being connected to the drive nut via an arbor extension and having a rotation axis that is substantially collinear with the long axis, wherein the arbor extension and the arbor are interconnected by a second engagement device that rotationally locks the arbor extension in an opposite direction when the arbor is rotated by the dose knob, wherein the arbor extension and the drive nut are interconnected by a third engagement device that rotationally locks but allows longitudinal movement of the drive nut in relation to the arbor extension;
• a spring force mechanism having a first end connected to the arbor and a second end connected to a fixed point on the chassis such that the spring force mechanism is tensioned when the dose knob and the arbor are rotated;
• and
• a guide part arranged with guide ledges which cooperate with longitudinal grooves of the plunger rod that rotationally locks but allows longitudinal movement of the plunger rod in relation to the guide part;
• and
• at least the power supply mechanism and rotating damping member cooperate to generate the pressure inside the medicament container that is substantially constant during medicament delivery;
• and rotation of the arbor rotates the rotating damping member.

A metered liquid droplet inhaling device for delivering medicament, comprising:

• a generally elongated tubular chassis having opposite distal and proximal ends;
• a medicament container holder releasably connected to the chassis by a first engagement device;
• a medicament container arranged inside the medicament container holder, wherein the container comprises a tubular form having at least one chamber configured for containing a composition, a proximal opening for allowing the composition to be expelled therefrom, and at least one axially movable piston that is coaxially movable along a long axis of the generally elongated tubular chassis;
• a dose knob accessible outside the distal end of the chassis for setting a dose to be expelled by accumulating a rotational force;
• a power supply mechanism configured for converting the rotational force into an axial force to be applied to the piston and thereby to create a pressure inside the medicament container;
• an activation device in mechanical connection to the power supply mechanism;
• a mouth piece mechanically connected to the proximal part of the container holder, wherein the mouth piece comprises a mouth engaging area and an air opening;
• a droplet generator having a plurality of through passing orifices and arranged in the mouth piece, wherein the orifices are in fluid communication with the proximal opening of the container and with the mouth piece;
• a rotating damping member mechanically connected to the power supply mechanism for damping an initial pressure peak inside the medicament container, wherein the rotating damping member comprises a distal part protruding into a compartment in the dose knob that is filled with a viscous material, wherein the distal part rotates about an axis that is coaxial with the long axis of the elongated tubular chassis, and the distal part being separated from the piston on the long axis;
• and
• a handling coordination mechanism configured for coordinating inhalation and delivery of medicament;
• wherein at least the power supply mechanism and rotating damping member cooperate to generate the pressure inside the medicament container that is substantially constant during medicament delivery.