Bioresorbable and biocompatible compounds for surgical use
AssigneeSofradim Production
InventorsPhilippe Gravagna, Yves Bayon, Sebastien Ladet
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Abstract
A bioresorbable and biocompatible compound for surgical use is composed of functionalized collagen cross-linked with a glycosaminoglycan.
Claims16
A compound comprising a functionalized collagen covalently bonded directly to chitosan without the use of a crosslinking agent, wherein the chitosan has a degree of acetylation from about 35 to 50% and wherein the collagen is functionalized by oxidative cleavage.
An implant comprising a compound containing a functionalized collagen covalently bonded directly to chitosan without the use of a crosslinking agent, wherein the chitosan has a degree of acetylation from about 35 to 50% and wherein the collagen is functionalized by oxidative cleavage.
A method of forming a bioresorbable compound comprising contacting a functionalized collagen with a glycosaminoglycan without the use of a crosslinking agent, wherein the glycosaminoglycan is chitosan having a degree of acetylation from about 35% to 50% and wherein the collagen is functionalized by oxidative cleavage, wherein a deionized water solution of functionalized collagen is combined to a deionized water solution of chitosan having a degree of acetylation from about 35% to 50% to allow the functionalized collagen to mix with the chitosan and form said compound.
Dependencies are inferred from the claim text.