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US 9,750,796 B2Granted
Cell wall polymers of Enterococcus faecalis and uses thereof
AssigneesUniversitaetsklinkum Freiburg, Forschungszentrum Borstel
InventorsJohannes Huebner, Otto Holst, Christian Theilacker, Karolina Kruszynska, Stefan Geiss-Liebisch, Agnieszka Beczala
Life of this patent
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Abstract
The present invention relates to enterococcal cell wall polymers and their uses in the prevention and therapy of bacterial infection.
Claims1
A method for inducing an immune response to Enterococcus faecalis in a subject, the method comprising administering, to the subject an enterococcal cell wall component or an antibody that specifically recognizes the enterococcal cell wall component, wherein the enterococcal cell wall component is β-D-GalpNAc-ribitol having the following structure:
- wherein R1 is selected from β-D-Glcp and α-L-Rhap, and
- R2 is selected from H and α-D-Glcp.
Dependencies are inferred from the claim text.