Terminalia chebula and Terminalia bellirica extracts for inhibition of xanthine oxidase
AssigneeNatreon, Inc.
InventorSanyasi R. Kalidindi
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Abstract
Compositions containing extracts of Terminalia chebula and Terminalia bellerica, or combinations thereof and methods for treatment of uricemia, hyperuricemia, and gout in a human subject are provided.
Claims11
A method of treating a free radical-induced disease in an individual in need thereof comprising administering to the individual a therapeutically effective amount of a composition consisting essentially of an aqueous extract of Terminalia bellirica,
- wherein the aqueous extract comprises at least 15% of one or more bioactive low molecular weight hydrolyzable tannins selected from the group consisting of chebulinic acid and chebulagic acid based on the total weight of the extract,
- wherein the administered composition inhibits xanthine oxidase activity, and
- wherein the free radical-induced disease is selected from the group consisting of gout, uricemia, and hyperuricemia.
A method of treating hyperuricemia in a human individual in need thereof comprising orally administering to the human individual a therapeutically effective amount of a composition consisting essentially of an aqueous extract of Terminalia bellirica,
- wherein the aqueous extract comprises at least 15% of one or more bioactive low molecular weight hydrolyzable tannins selected from the group consisting of chebulinic acid and chebulagic acid based on the total weight of the extract;
- and
- wherein the serum uric acid level in the individual is lowered.
Dependencies are inferred from the claim text.