Agents for promoting secretion and/or suppressing decrease of adiponectin

A method for accelerating the increase in or suppressing the decrease of adiponectin concentration, said method comprising:

• administering an effective amount of a culture supernatant of a microorganism selected from the group consisting of:
• Propionibacterium freudenreichii T004406 (CNCM I-3931), Propionibacterium freudenreichii subsp. freudenreichii DSM-20271T, and Propionibacterium freudenreichii subsp. shermanii DSM-4902T as an active ingredient to a subject in recognized need of accelerated increase in or suppressed decrease of adiponectin concentration;
• and
• accelerating the increase in or suppressing the decrease of adiponectin concentration in the subject.

A method for accelerating the increase in or suppressing the decrease of adiponectin concentration, said method comprising:

• administering an effective amount of a culture supernatant of a microorganism selected from the group consisting of:
• Propionibacterium freudenreichii T004406 (CNCM I-3931), Kluyveromyces lactis T001985 (CNCM I-3935), Propionibacterium freudenreichii subsp. freudenreichii DSM-20271T, Kluyveromyces lactis NBRC-1090T, Propionibacterium freudenreichii subsp. shermanii DSM-4902T, and Kluyveromyces marxianus JCM-1630T, as an active ingredient to a subject in recognized need of accelerated increase in or suppressed decrease of adiponectin concentration;
• and
• accelerating the increase in or suppressing the decrease of adiponectin concentration in the subject.

A method for promoting secretion or suppressing decrease of adiponectin, said method comprising:

• administering an effective amount of a culture supernatant of a microorganism selected from the group consisting of:
• Propionibacterium freudenreichii T004406 (CNCM I-3931), Kluyveromyces lactis T001985 (CNCM I-3935), Propionibacterium freudenreichii subsp. freudenreichii DSM-20271T, Kluyveromyces lactis NBRC-1090T, Propionibacterium freudenreichii subsp. shermanii DSM-4902T, and Kluyveromyces marxianus JCM-1630T, as an active ingredient to a subject in recognized need of promoted secretion or suppressed decrease of adiponectin;
• and
• promoting secretion or suppressing decrease of adiponectin concentration in the subject.

A method for promoting secretion or suppressing decrease of adiponectin, said method comprising:

• administering an effective amount of a culture supernatant of a microorganism selected from the group consisting of:
• Propionibacterium freudenreichii T004406 (CNCM I-3931), Propionibacterium freudenreichii subsp. freudenreichii DSM-20271T, and Propionibacterium freudenreichii subsp. shermanii DSM-4902T as an active ingredient to a subject in recognized need of promoted secretion or suppressed decrease of adiponectin;
• and
• promoting secretion or suppressing decrease of adiponectin in the subject.