Compositions and methods of using lamellar bodies for modifying linear biological macromolecules
AssigneeLamellar Biomedical Limited
InventorJames Dobbie
Life of this patent
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Abstract
Compositions comprising therapeutically effective amounts of lamellar bodies to restore lubricity and non-stick properties to mucous surfaces for conditions characterized by dry adherent surfaces, particularly those surfaces close to the body openings and conditions of the eye.
Claims18
A method of treating areas affected by mucositis to restore lubricity and non-stick properties to dry adherent surfaces or to decrease the viscosity of pathological exudates which can cause crusting and synechiae wherein the method comprises applying a composition including lamellar bodies in suspension to the mucous surfaces in a subject in need thereof wherein the lamellar bodies comprise about 44-70% phosphatidylcholine about 15-23% sphingomyelin about 6-10% phosphatidyl ethanolamine about 2-6% phosphatidyl serine about 2-4% phosphatidyl inositol and about 4-12% cholesterol by weight.
Dependencies are inferred from the claim text.