US 9,750,730 B2Granted

Apoptosis signal-regulating kinase inhibitor

AssigneeGilead Sciences, Inc.

InventorGregory Notte

Life of this patent

Estimating the term…

Abstract

The present invention relates to a compound of formula (I): The compound has apoptosis signal-regulating kinase (“ASK1”) inhibitory activity, and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis.

Claims10

Dependent claims

A method of treating liver fibrosis comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula (I)

or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 15/140,204Filed 27 Apr 2016 · division
Priority: 27 Jan 2012
Published: US 2016/0235728 A118 Aug 2016
Granted: 5 Sep 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification20 codes

C07D 401/14
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a…:…
A61K 9/0053
Galenical forms characterised by the site of application: mouth and digestive tract, i.e. intraoral and peroral administration
A61K 9/20
Medicinal preparations characterised by special physical form: pills, tablets, discs, rods
A61K 31/4439
Containing further heterocyclic ring systems: containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Family

Application61/591,710Us provisional application · filed 27 Jan 2012
Application13/748,901Parent of this division · filed 24 Jan 2013
Application14/254,359Parent of this division · filed 16 Apr 2014
US 2016/0235728 A1Pre-grant publication · published 18 Aug 2016
US 9,333,197 B2Parent of this division
US 8,742,126 B2Parent of this division
US 2013/0197037 A1Published application
US 2014/0228412 A1Published application
US 9,750,730 B2This patent

From the US filing history. Foreign family members aren’t listed.

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