Agents useful for treating obesity, diabetes and related disorders
AssigneeThe Regents of the University of California
InventorsGino Cortopassi, Alexey Tomilov
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Abstract
This invention provides methods of identifying agents useful to prevent, ameliorate or treat one or more symptoms of impaired insulin sensitivity, glucose tolerance, obesity, diabetes, aging, metabolic syndrome, or other metabolic syndrome component diseases, and methods of employing the identified agents to prevent, reduce, delay or inhibit one or more symptoms of impaired insulin sensitivity, glucose tolerance, obesity, diabetes, aging, metabolic syndrome, or other metabolic syndrome component diseases.
Claims20
A method of treating impaired insulin sensitivity, impaired glucose tolerance or obesity, comprising administering to a subject having the impaired insulin sensitivity, glucose tolerance or obesity an effective regime of idebenone as sole active agent, or a pharmaceutically acceptable salt thereof, thereby treating impaired insulin sensitivity, impaired glucose tolerance or obesity.
A method of treating impaired insulin sensitivity, impaired glucose tolerance or obesity, comprising co-administering to the subject having the impaired insulin sensitivity, glucose tolerance or obesity an effective regime of idebenone and Src I-1, or a pharmaceutically acceptable salt thereof, thereby treating impaired insulin sensitivity, impaired glucose tolerance or obesity.
Dependencies are inferred from the claim text.