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AssigneeGrüNenthal GmbH
InventorsEugeen Marie Jozef Jans, Filip René Irena Kiekens, Jody Firmin Marceline Voorspoels, Anne Faure, Iris Ziegler, Elisabeth Arkenau-Maric, Lutz Barnscheid, Johannes Bartholomäus, Marc Frevel, Eric Galia, Andrea Schüessele
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The invention relates to a pharmaceutical dosage form, preferably with controlled release of a pharmacologically active compound (A) contained therein, the pharmaceutical dosage form very preferably being tamper-resistant and most preferably having a breaking strength B1 of at least 500 N in direction of extension E1 and having a breaking strength B2 of less than 500 N in direction of extension E2.
A pharmaceutical dosage form with controlled release of a pharmacologically active compound (A) contained therein, the pharmaceutical dosage form having a first breaking strength (B1) of at least 500 N in a first direction of extension (E1) and having a second breaking strength (B2) of less than 500 N in a second direction of extension (E2), wherein the pharmacologically active compound (A) is tapentadol or a physiologically acceptable salt thereof and/or the pharmaceutical dosage form comprises a polyalkylene oxide.
Dependencies are inferred from the claim text.