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US 9,750,700 B2Granted
Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
AssigneeNatco Pharma Limited
InventorsKali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
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Abstract
The invention relates to an oral pharmaceutical composition comprising, greater than 80% of Imatinib, by weight based on the total weight of the composition and the process for preparation thereof.
Claims5
A tablet composition comprising an intragranular and an extragranular portion;
- at least 97% Imatinib mesylate by weight based on the total weight of the tablet composition;
- and
- a lubricant, wherein
- the lubricant is present in the extragranular portion of the tablet composition;
- and
- the lubricant is sodium stearyl fumarate.
3 more elements
A process for the preparation of a tablet composition comprising at least 97% Imatinib mesylate by weight based on the total weight of the tablet composition, wherein the tablet composition comprises an intragranular and an extragranular portion, said process comprising wet granulation;
- wherein
- a lubricant is present in the extragranular portion of the tablet composition;
- and
- the lubricant is sodium stearyl fumarate.
1 more element
Dependencies are inferred from the claim text.