Antifungal compositions for the treatment of skin and nails

A method for treating a skin disease complicated by microbial colonization or infection, said method comprising:

• (a) providing a pharmaceutically acceptable composition comprising
• 0.1% to 10% (w/w) of a therapeutic agent which is povidone-iodine (PVP-I) wherein the 0.1% to 10% PVP-I is dissolved in
• greater than 33% (w/w) DMSO and at least one co-solvent;
• and a pharmaceutically acceptable carrier which is a gel to form a gel composition;
• and
• (b) topically administering the composition to a patient in need of treatment of the skin disease, wherein the skin disease is molluscum contagiosum.