Massively parallel diffuse optical tomography

A system for generating a volumetric image of a sample, the system comprising:

• an optical emitter system that emits an intensity-modulated first transillumination beam towards a portion of the sample;
• a plurality of sensor systems comprising sensors each having a plurality of individual pixels and positioned at different respective locations about the sample, the plurality of sensor systems configured to demodulate light from the intensity-modulated first transillumination beam emerging from the sample within a field of view of each sensor and directed toward the sensors, the demodulation occurring in parallel among the intensity-modulated first transillumination beam corresponding to the plurality of pixels of each sensor, wherein the individual pixels are exposed to a demodulated transillumination beam instead of the intensity-modulated first transillumination beam, and wherein the individual pixels detect, in parallel, demodulated respective portions of the intensity-modulated first transillumination beams that exit the sample in the fields of view of the respective sensor systems, the plurality of sensor systems further configured to output respective electrical signals based on the demodulated transillumination beam instead of the intensity-modulated first transillumination beam, wherein the respective electrical signals include volumetric information obtained from the demodulation;
• and
• a computing apparatus in communication with the plurality of sensor systems, the computing apparatus receives the electrical signals output by the respective sensor systems and generates the volumetric image of the sample based upon the electrical signals.