Blood coagulation system analyzer, and blood coagulation system analysis method and program

A blood coagulation system analysis method comprising:

• applying an alternating voltage to a pair of electrodes that are opposed to each other and inserted into opposite ends of a cylinder;
• measuring permittivity of a sample of whole blood which is positioned between the pair of electrodes;
• analyzing a degree of the action of a blood coagulation system by determining the permittivity of blood measured at predetermined time intervals after an anticoagulant effect acting on the sample of whole blood is ended,
• wherein the determination of the anticoagulant effect acting on the sample of whole blood is ended is determined when the permittivity of blood is equal to or greater than the predetermined threshold,
• wherein the analyzing includes estimating a viscoelasticity manifestation timing at which viscoelastic characteristics are exhibited and obtaining a gradient of a straight line as a parameter showing an amount of increase in permittivity of a frequency to be considered within a predetermined time period after the anticoagulant effect acting on the sample of whole blood is ended, and
• wherein the analyzing includes dividing permittivity of a first frequency and permittivity of a second frequency, different from the first frequency, within a predetermined time period after the anticoagulant effect acting on the sample of whole blood is ended by expressing them as a ratio between the permittivity and permittivity at a reference time to analyze, using the division result, the degree of the action of the blood coagulation system;
• and
• displaying the estimated viscoelasticity manifestation timing at which viscoelastic characteristics predict that the sample of whole blood starts to clot to monitor patient disease.

A non-transitory computer-readable medium storing computer-readable instructions thereon, the computer-readable instructions when executed by a computer cause the computer to perform a method comprising:

• applying an alternating voltage to apply an alternating voltage to a pair of electrodes that are opposed to each other and inserted into opposite ends of a cylinder;
• measuring permittivity to measure permittivity of a sample of whole blood which is positioned between the pair of electrodes;
• analyzing a blood coagulation system to analyze a degree of the action of a blood coagulation system by determining the permittivity of blood which is measured at predetermined time intervals after an anticoagulant effect acting on the sample of whole blood is ended,
• wherein the determination of the anticoagulant effect acting on the sample of whole blood is ended is determined when the permittivity of blood is equal to or greater than the predetermined threshold,
• wherein the analyzing includes estimating a viscoelasticity manifestation timing at which viscoelastic characteristics are exhibited and obtaining a gradient of a straight line as a parameter showing an amount of increase in permittivity of a frequency to be considered within a predetermined time period after the anticoagulant effect acting on the sample of whole blood is ended, and
• wherein the analyzing includes dividing permittivity of a first frequency and permittivity of a second frequency, different from the first frequency, within a predetermined time period after the anticoagulant effect acting on the sample of whole blood is ended by expressing them as a ratio between the permittivity and permittivity at a reference time to analyze, using the division result, the degree of the action of the blood coagulation system;
• and
• displaying the estimated viscoelasticity manifestation timing at which viscoelastic characteristics predict that the sample of whole blood starts to clot to monitor patient disease.