Method for assaying plasminogen in a liquid medium, associated compositions and kit
AssigneeSysmex Corporation
InventorJean Amiral
Life of this patent
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Abstract
The invention relates to a method for assaying plasminogen in a sample comprising a step consisting in particular of reacting a streptokinase (R1), and a streptokinase activator, with a control solution or a diluted plasma sample, in which the streptokinase activator is selected from the group comprising a fibrin DD fragment and/or at least one DD fragment derivative. The invention also relates to a liquid composition, a plasminogen assay kit for implementing this method and the use of a streptokinase activator selected from the group comprising a fibrin DD fragment and/or at least one DD fragment derivative.
Claims12
A method for assaying plasminogen in a sample comprising steps consisting of:
- a) storing a composition comprising a streptokinase and a streptokinase activator in a ready-to-use solution;
- b) reacting the composition with a control solution or a diluted plasma sample;
- c) tracking said reaction;
- d) determining the amount of plasminogen in the control solution or in the diluted plasma sample, as a function of the result of the tracking of said reaction, wherein the streptokinase activator is a fibrin DD fragment, at least one DD fragment derivative, or both a fibrin DD fragment and at least one DD fragment derivative.
A method for assaying plasminogen in a sample comprising:
- storing a composition comprising streptokinase and a streptokinase activator in a ready-to-use solution;
- reacting the composition with a control solution or a diluted plasma sample;
- tracking the reaction of the streptokinase and the streptokinase activator with the control solution of the diluted plasma sample;
- and
- determining an amount of plasminogen in the control solution or in the diluted plasma sample based on the result of the tracking of the reaction,
- wherein the streptokinase activator is at least one selected from the group consisting of a fibrin DD fragment and at least one DD fragment derivative.
Dependencies are inferred from the claim text.