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US 9,517,241 B2Granted
Amelioration of intestinal fibrosis and treatment of Crohn's disease
AssigneeThe Regents of the University of Michigan
InventorsRobert U. Simpson, Peter D. R. Higgins, Laura A. Johnson
Life of this patent
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Abstract
Methods of treating patients with inflammatory bowel disease, intestinal fibrosis, or Crohn's disease involve administering a therapeutic amount of CARD-024 or related compound.
Claims18
A method of ameliorating intestinal fibrosis in a subject, the method comprising administering to the subject a composition comprising a compound of Formula (I)
- wherein Et is ethyl,
- wherein the dashed line indicates a single bond or a double bond in the E configuration between carbon 22 and carbon 23, and
- wherein the configuration at carbon 24 to which Et is attached is in the R configuration or the S configuration.
Dependencies are inferred from the claim text.