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US 9,517,228 B2Granted
Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes
AssigneeJenrin Discovery
InventorsJohn F McElroy, Robert J Chorvat
Life of this patent
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Abstract
The present invention provides novel, diastereomeric pyrazolines that are useful as cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, inflammatory disorders, cardiometabolic disorders, hepatic disorders, and/or cancers.
Claims18
A method of treating a disease, comprising:
- administering to a mammal in need thereof a therapeutically effective amount of a compound selected from the compounds 1, 2, 3, and 4:
- or a pharmaceutically acceptable salt thereof, wherein the disease is hepatocellular carcinoma.
Dependencies are inferred from the claim text.