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US 9,517,220 B2Granted
Bromfenac bioavailability
AssigneeBausch & Lomb Pharma Holdings Corp.
InventorsAngel Padilla, George Baklayan
Life of this patent
Estimating the term…
Abstract
Formulations and methods that provided enhanced bromfenac penetration into ocular tissue when topically administered, compared to the currently available BROMDAY™ formulation and method when topically administered. The formulations and methods did so while retaining the patient convenience of a once-daily administration and advantageously lowered the bromfenac concentration dosed to the patient.
Claims18
A method for treating an ocular condition in a patient in need thereof with bromfenac, the method comprising
- administering bromfenac as the only active 0.07% w/v in a composition at a pH≧6.0 and pH<8.0 and containing 1.0% povidone, topically to the eye of the patient, enhancing bromfenac penetration into ocular tissue to provide the same or better therapy than a higher bromfenac concentration.
Dependencies are inferred from the claim text.