Multi-functional option valve, multifunctional fully automatic liquid chromatography system including the same, and method for analyzing sample using the same

A multifunction selection apparatus having multiple ports to which both ends of a 1st dimension separation column are connected at one part thereof and both ends of a titanium dioxide column are connected at another part thereof,

• the multiple ports comprising an inlet port, an outlet port, a first connecting port and a second connecting port linked individually to each end of the 1st dimension separation column, and a first titanium dioxide column-connecting port and a second titanium dioxide column-connecting port linked individually to each end of the titanium dioxide column,
• the multifunction selection apparatus further comprising:
• a fluid passing mode in which a fluid introduced thereto is not passed through the 1st dimension separation column but is discharged, the inlet port is directly and fluidically communicated with the outlet port in the fluid passing mode;
• a column passing mode in which the fluid introduced thereto is passed through the 1st dimension separation column and then discharged, the inlet port is fluidically communicated with the first connecting port of the 1st dimension separation column and the outlet port is fluidically communicated with the second connecting port of the 1st dimension separation column in the column passing mode;
• a fluid blocking mode in which the fluid is prevented from being introduced, the inlet port and the outlet port are fluidically interrupted with each other in the fluid blocking mode;
• and
• a titanium dioxide column passing mode in which the fluid introduced thereto is passed through the titanium dioxide column and then discharged, the inlet port is fluidically communicated with the first titanium dioxide column-connecting port and the outlet port is fluidically communicated with the second titanium dioxide column-connecting port, in the titanium dioxide column passing mode,
• wherein the multiple ports further comprise a first, a second and a third selection ports;
• the first selection port is fluidically communicated with the second titanium dioxide column-connecting port and the second selection port is fluidically communicated with the third selection port, in the fluid passing mode;
• the first selection port is fluidically communicated with the second titanium dioxide column-connecting port and the second selection port is fluidically communicated with the third selection port, in the column passing mode;
• the first titanium dioxide column-connecting port is closed, in the fluid blocking mode;
• and
• the first selection port is fluidically communicated with the first connecting port of the 1st dimension separation column and the third selection port is fluidically communicated with the second connecting port of the 1st dimension separation column, in the titanium dioxide column passing mode.