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US 9,434,926 B1Granted
Graphene hydrogel and methods of using the same
AssigneeUniversity of South Florida
InventorsSubhra Mohapatra, Chunyan Wang
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Abstract
Provided herein are hydrogel compositions containing graphene, chitosan, a polyethylene (glycol) diacrylate (PEGDA). The hydrogel can optionally contain an N-isopropylacrylamide (NIPAM) (TPCG hydrogel). Also provided are methods for differentiating a cell on the hydrogels described herein. Further provided herein are methods for delivering a compound via the hydrogels described herein.
Claims21
A method comprising:
- contacting a cell with a hydrogel for a period of time, where the hydrogel comprises:
- at least two acrylated chitosan-graphene monomers, where each chitosan-graphene monomer comprises:
- carboxylic acid functionalized graphene, where the chitosan component of the chitosan-graphene monomer is covalently bonded to the carboxylic acid functionalized graphene component of the chitosan-graphene monomer;
- and
- polyethylene (glycol) diacrylate (PEGDA), where the (PEGDA) covalently crosslinks the at least two acrylated chitosan-graphene monomers.
2 more elements
Dependencies are inferred from the claim text.