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US 9,434,729 B2Granted
Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
AssigneeCellix Bio Private Limited
InventorMahesh Kandula
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Abstract
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of periodontitis and rheumatoid arthritis may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.
Claims13
A compound of Formula I:
- or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, or stereoisomer thereof, wherein:
- R1 represents —CH2—, —CH2O—,
- R2 represents D,
- a is 2, 3 or 7;
- each b is independently 3, 5 or 6;
- e is 1, 2 or 6;
- c and d are each independently H, D, —OH, —OD, C1-C6-alkyl, —NH2 or —COCH3;
- and
- n is 0, 1, 2, 3, 4 or 5.
6 more elements
Dependencies are inferred from the claim text.