Universal portable artificial kidney for hemodialysis and peritoneal dialysis

A method of performing peritoneal dialysis comprising:

• flowing dialysate along a first flow path through a manifold and into a dialysate reservoir, the manifold comprising a manifold body that defines a plurality of internal passageways and a plurality of ports providing fluid communication to fluid passageways external to the manifold body, the manifold further comprising a first pumping tube, a second pumping tube, and a third pumping tube each in fluid communication with the plurality of internal passageways, the plurality of internal passageways partially defining each of the first flow path, a second flow path, a third flow path, and a fourth flow path, the first flow path including the first pumping tube;
• weighing the dialysate in the dialysate reservoir to obtain a first weight;
• flowing the dialysate out of the reservoir, along the second flow path through the manifold, and into a peritoneal cavity, the second flow path including the second pumping tube;
• flowing the dialysate out of the peritoneal cavity, along the third flow path through the manifold, and into a drain reservoir, the third flow path including the third pumping tube;
• weighing the dialysate in the drain reservoir to obtain a second weight;
• and
• flowing the dialysate out of the drain reservoir and along the fourth flow path through the manifold, the fourth path also including the third pumping tube,
• wherein the flowing the dialysate along the third flow path comprises pumping the dialysate through the third pumping tube in a first direction, and the flowing the dialysate along the fourth flow path comprises pumping the dialysate through the third pumping tube in a second direction that is opposite the first direction.