US 9,433,689 B2 · Probes and methods of imaging non-Hodgkins lymphoma

Abstract

Embodiments of the present disclosure provide for labeled probes such as a 64Cu-FN3 probe (FN3 refers to fibronectin type 3 domain); methods of making labeled probes; pharmaceutical compositions including labeled probes; methods of using labeled probes; methods of diagnosing, localizing, monitoring, and/or assessing non-Hodgkin's lymphoma, cancers, tumors, precancerous cells, and related biological events using labeled probes; kits for diagnosing, localizing, monitoring, and/or assessing non-Hodgkin's lymphoma, cancers, tumors, precancerous cells, and related biological events; and the like.

Claims19

Dependent claims

A method of diagnosing the presence of a non-Hodgkin's lymphoma in a subject, the method comprising:

administering to the subject a labeled probe with a sequence having SEQ. ID. NO.:
2 or SEQ. ID. NO.:
4, wherein the probe binds to a CD20 protein;
imaging at least a portion of the subject;
and
detecting the labeled probe, wherein the location of the labeled probe corresponds to the location of the non-Hodgkin's lymphoma.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application

14/204,039Filed 11 Mar 2014 · us provisional application

Priority

12 Mar 2013

Published

US 2014/0271467 A118 Sep 2014

Granted

6 Sep 2016

Term ends

Not estimatedThe source records don’t support an estimate.

Classification2 codes

A61K 51/088
Peptides, e.g. proteins , carriers being peptides, polyamino acids, proteins: conjugates with carriers being peptides, polyamino acids or proteins
A61K
Medicines and medical preparations

Probes and methods of imaging non-Hodgkins lymphoma

Life of this patent

Probes and methods of imaging non-Hodgkins lymphoma

Life of this patent

Abstract

Claims19