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US 9,433,676 B2Granted
Hair removal with nanoparticles with coatings that facilitate selective removal from the skin surface
AssigneeSienna Biopharmaceuticals, Inc.
InventorsTodd James Harris, Alice Ann Chen Kim
Life of this patent
Estimating the term…
Abstract
Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans. In particular, embodiments of hair removal with nanoparticles with coatings that facilitate selective removal from the skin Surface are disclosed.
Claims20
A method of treating a hair follicle, comprising:
- pre-treating a skin surface to increase delivery of plasmonic nanoparticles to a hair follicle
- applying a composition of plasmonic nanoparticles to the skin surface,
- distributing a portion of the composition of from the skin surface to the hair follicle while a remaining portion of the composition is left on the skin surface;
- wherein the nanoparticles have a concentration selected from the group consisting of:
- 109, 1010, 1011, 1012, and 1013 particles per ml of the composition,
- wherein the nanoparticles are unassembled,
- wherein the plasmonic nanoparticles comprise at least one of gold, silver, and platinum,
- wherein the plasmonic nanoparticles comprise a coating, wherein said coating facilitates selective removal from the skin surface,
- selectively removing the remaining portion of the composition from the skin surface, and
- exposing the composition of plasmonic nanoparticles to an energy wavelength selected from the group consisting of:
- 755 nm, 800-810 nm, and 1064 nm, thereby localizing thermal damage to said hair follicle for at least one of hair removal or hair growth reduction.
8 more elements
A method of localizing thermal damage to a hair follicle, comprising:
- topically applying a composition of nanoparticles to a skin surface,
- wherein the nanoparticles comprise a conductive metal portion,
- wherein the conductive metal portion comprises at least one of gold, silver, and platinum,
- wherein the nanoparticles comprise a coating that coats the conductive metal portion, wherein said coating facilitates selective removal from the skin surface;
- wherein the nanoparticles have a concentration selected from the group consisting of:
- 109, 1010, 1011, 1012, and 1013 particles per ml of the composition,
- wherein said concentration is sufficient to, after exposure an energy wavelength, induce thermal damage in a hair follicle;
- wherein the nanoparticles are unassembled,
- distributing a portion of the composition from the skin surface to the hair follicle while a remaining portion of the composition is left on the skin surface;
- selectively removing the remaining portion of the composition from the skin surface;
- and
- exposing the composition with an energy wavelength selected from the group consisting of:
- 755 nm, 800-810 nm, and 1064 nm, thereby inducing a surface plasmon in said nanoparticles, thereby localizing thermal damage to said hair follicle for at least one of hair removal or hair growth reduction.
10 more elements
A method of localizing thermal damage to a hair follicle, comprising:
- providing a composition of nanoparticles configured for topical application to a skin surface;
- wherein the composition of nanoparticles has at least one peak absorption wavelength,
- wherein the nanoparticles have a concentration selected from the group consisting of:
- 109, 1010, 1011, 1012, and 1013 particles per ml of the composition, wherein the nanoparticles are unassembled,
- wherein the nanoparticles comprise a conductive metal portion,
- wherein the conductive metal portion comprises at least one of gold, silver, and platinum,
- wherein the nanoparticles comprise a coating that coats the conductive metal portion, wherein said coating facilitates selective removal from the skin surface;
- targeting a hair follicle by redistributing a portion of the composition of nanoparticles from the skin surface to the hair follicle while a remaining portion of the composition is left on the skin surface;
- selectively removing the remaining portion of the composition from the skin surface;
- and
- exposing the composition of nanoparticles to an energy source to induce a surface plasmon in said nanoparticles, thereby localizing thermal damage to said hair follicle for at least one of hair removal or hair growth reduction.
8 more elements
Dependencies are inferred from the claim text.