Schmallenberg virus (SBV) vaccine, methods of production, and uses thereof
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsVeljko Nikolin, Konrad Stadler, Axel Lischewski, Alexander Brix, Jeffrey P. Knittel, Katharina Hedwig Toepfer
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Abstract
The present invention relates to the field of vaccines and medicaments for the prophylaxis and treatment of infectious diseases in ruminants. In particular, it relates to inactivated Schmallenberg virus (SBV) useful as vaccine or medicament for preventing or treating viremia, the transmission and clinical symptoms, in particular malformations in newborn ruminants such as cattle, sheep and goats, induced by SBV.
Claims19
An immunogenic composition comprising saponin, aluminum hydroxide, and an aziridine compound-inactivated Schmallenberg virus (SBV), wherein the inactivated SBV comprises a medium (M) RNA segment having a sequence that is inverse complementary to a nucleic acid sequence having at least 95% sequence identity with the nucleic acid sequence of SEQ ID NO:2 over the whole length of SEQ ID NO:2.
Dependencies are inferred from the claim text.