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US 9,359,410 B2Granted
Virus like particle purification
AssigneeTakeda Vaccines, Inc.
InventorsThomas S. Vedvick, Bryan Steadman, Charles Richardson, Thomas R. Foubert, Charles R. Petrie
Life of this patent
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Abstract
Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
Claims13
A method of purifying Calicivirus virus-like particles (VLPs) comprising contacting a solution containing said VLPs with at least one chromatographic material, wherein the at least one chromatographic material is an ion exchange chromatographic material, wherein the chromatographic materials used in the method do not comprise hydroxyapatite, and wherein the VLPs are purified to greater than about 70%.
Dependencies are inferred from the claim text.