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US 9,353,152 B2Granted
Induction of the mitochondrial permeability transition
AssigneeNewSouth Innovations Pty Limited
InventorPhilip John Hogg
Life of this patent
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Abstract
The present invention relates to process for identifying a compound which induces the mitochondrial permeability transition (MPT) in proliferating cells, wherein said process comprises contacting a cell or cell extract with a compound, determining whether the compound binds to adenine nucleotide translocator (ANT), and determining whether the compound selectively induces the MPT in proliferating cells.
Claims2
A compound selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.