Sorbent for a dialysis device
AssigneeTemasek Polytechnic
InventorsChristian Gert Bluchel, Yanmei Wang, Kim Cheng Tan
Life of this patent
Estimating the term…
Abstract
There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.
Claims11
A fixed bed sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a primary layer of urease particles covalently immobilized on a biocompatible material intermixed with cation exchange particles and anion exchange particles,
- wherein the cation exchange particles are zirconium phosphate particles and the anion exchange particles are zirconium oxide particles,
- wherein a pressure drop of the dialysis liquid across the primary layer is dependent on the size of said cation exchange particles;
- and
- wherein said urease uremic toxin-treating enzyme particles, said anion exchange particles and said cation exchange particles are, when in use, in direct contact with the dialysis liquid.
A fixed bed sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of urease particles covalently immobilized on a biocompatible material intermixed with cation exchange particles having an average particle size in the range of 50 microns to 200 microns and anion exchange particles;
- wherein the cation exchange particles are zirconium phosphate particles and the anion exchange particles are zirconium oxide particles, and
- wherein said urease particles, said anion exchange particles and said cation exchange particles are, when in use, in direct contact with the dialysis liquid.
Dependencies are inferred from the claim text.