Activated pH control for protein glues
AssigneeEmpire Technology Development LLC
InventorsEzekiel Kruglick, Seth Miller
Life of this patent
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Abstract
A glue composition can include: one or more glue proteins selected to undergo a conformational change responsive to a pH change; and one or more pH components selected to change the pH of the one or more glue proteins in response to a change in one or more conditions. The glue can be prepared by: providing one or more glue proteins selected to undergo a conformational change in response to a pH change; and combining the glue proteins with one or more pH components selected to change the pH of the one or more glue proteins in response to a change in one or more conditions.
Claims25
A liquid glue composition comprising:
- one or more glue proteins selected to undergo a conformational change from a substantially folded conformation to a substantially unfolded conformation responsive to a pH change;
- an aqueous medium;
- and
- one or more pH components selected to change the pH of the glue composition in response to a change in one or more conditions, the one or more pH components are a combination of an anionic surfactant and an anionic base;
- wherein the glue composition having the one or more glue proteins in the substantially folded conformation, aqueous medium, and one or more pH components is a storage stable liquid in a first condition at a pH of about 6-8 prior to the change in one or more conditions, wherein the glue composition is in the first condition and is below a critical micelle concentration.
Dependencies are inferred from the claim text.