Analytical methods
AssigneeHarvard Apparatus Regenerative Technology, Inc.
InventorRon Sostek
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Abstract
Aspects of the disclosure provide techniques for detecting differences and/or changes in biological and non-biological material using infrared imaging. Aspects of the disclosure are useful for monitoring and evaluating synthetic scaffolds and engineered tissue and organs for tissue engineering and transplantation.
Claims35
A method of detecting a physical or functional property of a biological object, the method comprising:
- detecting a first infrared emission from a first site of the biological object,
- identifying a contrast between the first infrared emission and a second infrared emission, wherein the contrast is indicative of the physical or functional property, and wherein the first infrared emission is detected while the biological object is present in a subject.
A method of detecting a physical or functional property of a biological object, the method comprising:
- detecting a first infrared emission from a first site of the biological object,
- identifying a contrast between the first infrared emission and a second infrared emission, wherein the contrast is indicative of the physical or functional property, and wherein the first infrared emission is detected while the biological object is present in a bioreactor.
A method of detecting a physical or functional property of an engineered tissue or organ, the method comprising:
- detecting a first infrared emission from a first site of the engineered tissue or organ,
- identifying a contrast between the first infrared emission and a second infrared emission, wherein the contrast is indicative of a physical or functional property, and wherein the first site comprises at least a portion of a conduit of the engineered tissue or organ.
A method of detecting a physical or functional property of an engineered tissue or organ, the method comprising:
- detecting a first infrared emission from a first site of the engineered tissue or organ,
- identifying a contrast between the first infrared emission and a second infrared emission, wherein the contrast is indicative of a physical or functional property, and wherein the physical or functional property is an extent of hydration or vascularization of the engineered tissue or organ.
Dependencies are inferred from the claim text.