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US 9,040,703 B2Granted
Inhibitors of arginase and their therapeutic applications
AssigneeMars, Incorporated
InventorsMichael Van Zandt, Adam Golebiowski, Min Koo Ji, Darren Whitehouse, Todd Ryder, Paul Beckett
Life of this patent
Estimating the term…
Abstract
Compounds according to Formula I and Formula II are potent inhibitors of Arginase I and II activity: where R1, R2, R3, R4, R5, R6, R7, R8, R9, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.
Claims2
The compound according to the following structure:
- or a pharmaceutically acceptable salt, tautomer, or prodrug thereof.
Dependencies are inferred from the claim text.