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US 9,040,581 B1Granted
Methods of treatment using D-serine
AssigneeThe Florida State University Research Foundation, Inc.
InventorSanjay Kumar
Life of this patent
Estimating the term…
Abstract
Methods of treatment using D-serine to target brain cells expressing GluN3 subunit-containing triheteromeric NMDARs are disclosed. The methods include inhibiting calcium ion uptake by brain cells, treating epilepsy, and treating seizures by artificially administering D-serine.
Claims20
A method of inhibiting calcium ion uptake by brain cells, the method comprising artificially administering D-serine to brain cells expressing GluN3 subunit-containing triheteromeric NMDARs, the amount of D-serine being effective to inhibit calcium ion uptake by the cells.
Dependencies are inferred from the claim text.