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AssigneeElanco Animal Health Ireland Limited
InventorsPeter Frank Ekhart, Mario Van Wandelen, Jan Matthijs Jetten
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This invention concerns a method for the preparation of a suspoemulsion formulation, which can be easily produced on an industrial scale and which allows the reproducible and effective administration of one or more water-insoluble veterinary drugs through water distribution systems. The water-insoluble veterinary drug, in finely ground form, is dispersed in a water immiscible liquid, followed by homogenization of this system into a water phase. To facilitate the preparation of a stable formulation, one or more stabilizing agents such as emulsifiers, thickeners, anti-oxidants and anti-microbials can be used. The resulting suspoemulsion shows excellent long term storage stability and a good “in use” stability after dilution in a vessel and during all handling and transport in the water distribution system.
A method of preparing a suspoemulsion suitable, optionally after dilution, for administering flubendazole through a water distribution system, comprising mixing flubendazole with a water-immiscible liquid in such a manner that the mixture of active compound and water-immiscible liquid has a density between 0.85 and 1.2, and suspending said mixture in an aqueous carrier.
A suspoemulsion suitable, optionally after dilution, for administering flubendazole through a water distribution system, comprising a homogeneous suspension in water of a mixture of the flubendazole and a water-immiscible liquid, said mixture having a density between 0.85 and 1.2.
Dependencies are inferred from the claim text.