6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD

A compound of the formula

• wherein
• q is 0, 1 , or 2;
• s is 0, 1 , or 2;
• R3, each time taken, is independently selected from the group consisting of hydrogen, hydroxyl, amino, C1-8 alkylamino, cyano, halo, C1-6 alkyl, and C1-4 alkoxy;
• R4 is selected from the group consisting of hydrogen, cyano, halo, methyl, ethyl, methoxy, and trifluoromethyl;
• R5 is selected from the group consisting of
• R6, each time taken, is independently selected from the group consisting of hydrogen, cyano, halo, C3-8 cycloalkyl, C1-6 alkyl, C1-4 alkoxy, and trifluoromethyl;
• R7 is selected from the group consisting of cyano and cyanomethyl;
• R8, each time taken, is independently selected from the group consisting of hydrogen, cyano, halo, C1-4 alkyl, C1-4 alkoxy, and trifluoromethyl;
• R9 is selected from the group consisting of hydrogen, C1-6 alkyl optionally substituted with 1 to 3 fluoro, and C3-8 cycloalkyl;
• or a pharmaceutically acceptable salt thereof.