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US 9,040,257 B2Granted
Basidiomycetous yeast mutant
AssigneesToyobo Co., Ltd., National Research Institute of Brewing
InventorsYuu Utashima, Takahide Kishimoto, Shusaku Yanagidani, Kazuo Masaki
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Abstract
The present invention provides a host for genetic recombination useful in the production of heterologous proteins in a large scale, by suppressing the production of extracellular polysaccharides in the basidiomycetous yeasts. Cryptococcus sp. S-2 D11 strain (FERM BP-11482) which is characterized in that the production of extracellular polysaccharides is suppressed as compared with the parent strain.
Claims2
A Cryptococcus strain deposited as FERM BP-11482.
A method for producing a target protein, comprising:
- transforming a gene of the target protein to a Cryptococcus strain deposited as FERM BP-11482,
- culturing the resulting transformant, and
- collecting the target protein from the resulting culture product.
Dependencies are inferred from the claim text.