Back to results
US 9,040,250 B2Granted
Binding interaction of proanthocyanidins with bacteria and bacterial components
AssigneeThe United States of America as represented by the Secretary of the Navy
InventorsJames B Delehanty, Brandy J White, Baochuan Lin, Frances S Ligler
Life of this patent
Estimating the term…
Abstract
A composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6. A method of administering to an immunosuppressed patient or a patient diagnosed with sepsis or septic shock a composition having a proanthocyanidin. A method of administering to a patient diagnosed with a gram negative bacterial infection a composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6.
Claims10
A composition comprising:
- a plurality of proanthocyanidin compounds having more than one degree of polymerization;
- wherein the average degree of polymerization of all the proanthocyanidins in the composition is from 20 to 22;
- and
- wherein the composition comprises a proanthocyanidin compound containing at least one A-type linkage.
1 more element
A method comprising:
- administering to an immunosuppressed patient or a patient diagnosed with sepsis or septic shock a composition comprising a plurality of proanthocyanidin compounds having more than one degree of polymerization and containing at least one A-type linkage;
- wherein the average degree of polymerization of all the proanthocyanidins in the composition is from 20 to 22.
A method comprising:
- administering to a patient diagnosed with a gram negative bacterial infection a composition comprising a plurality of proanthocyanidin compounds having more than one degree of polymerization and containing at least one A-type linkage;
- wherein the average degree of polymerization of all the proanthocyanidins in the composition is from 20 to 22.
Dependencies are inferred from the claim text.