Frozen compositions and methods for piercing a substrate

A frozen piercing implement, comprising:

• at least one sterile frozen ice microneedle approximately one centimeter or less, extending substantially outward from a planar support structure and including a glucose sensor located within the sterile frozen ice microneedle;
• wherein the frozen ice microneedle is configured for piercing a substrate, and is externally coated in at least one of a therapeutic agent, abrasive, reinforcement agent, biological remodeling agent or explosive material.