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US 9,040,072 B2Granted
Use of coupling agents to improve the interface in absorbable polymer composites
AssigneeEthicon, Inc.
InventorsYue Zhou, Kevin Cooper, Yufu Li, Zhigang Li
Life of this patent
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Abstract
A composite having a poly(ethylene-co-acrylic acid) coupling agent, a filler, and a biocompatible, biodegradable polymer matrix is disclosed. The composites are useful for biomedical applications such as, tissue engineering, drug delivery, and implantable medical devices.
Claims12
A composite comprising:
- a beta-tricalcium phosphate filler comprising coated particles, each particle having an outer surface, and a copolymer of poly (lactic acid);
- a coating comprising a 20:80 mole:
- mole poly (ethylene-co-acrylic) coupling agent, said coating deposited on the outer surface of the particles;
- and,
- a poly (glycolic acid) polymer matrix.
2 more elements
A composite comprising:
- a beta-tricalcium phosphate filler comprising coated particles, each particle having an outer surface;
- and,
- a coating comprising a poly (ethylene-co-acrylic) coupling agent, said coating deposited on the outer surface of the particles;
- and,
- a copolymer of poly (lactic acid) and poly (glycolic acid) polymer matrix wherein the polymer matrix comprises about 95 wt % of the total weight of the composite.
2 more elements
A medical device, comprising:
- a composite, said composite comprising:
- a beta-tricalcium phosphate filler comprising coated particles, each particle having an outer surface, and a polymer of poly (lactic acid);
- a coating comprising a 20:80 mole:
- mole poly (ethylene-co-acrylic) coupling agent, said coating deposited on the outer surface of the particles;
- and,
- a poly (glycolic acid) polymer matrix.
3 more elements
Dependencies are inferred from the claim text.