High pressure mass spectrometry systems and methods

A mass spectrometer, comprising:

• a support base comprising a first plurality of electrodes, a pump, and a mounting member;
• and
• a pluggable module comprising:
• a second plurality of electrodes;
• an ion source;
• and
• an ion trap,
• wherein the pluggable module is configured to releasably connect to the support base by:
• engaging the second plurality of electrodes with the first plurality of electrodes;
• and
• engaging the mounting member to form a continuous fluid path extending from the pump through internal regions of the ion trap and the ion source;
• and
• wherein the pump is configured so that during operation of the mass spectrometer:
• the pump maintains a pressure of gas particles in the ion trap, in the ion source, and in an ion detector in a range from 100 mTorr to 100 Torr;
• and
• the pump maintains pressures of gas particles in the ion trap, in the source, and in the ion detector that differ by less than 10 mTorr.