Dihydroorotate dehydrogenase inhibitors

A compound of formula II:

• wherein,
• R1 denotes COOH, COOA, cyano, tetrazolyl, CON(R3)2 or CONHA;
• R2 denotes H, Hal or A;
• Ra is selected from the group consisting of:
• X1, X2 denote each independently of one another NRc or NRd, and provided that one of X1 and X2 is NRd and the other is NRc;
• Rb and Rc together represent a chemical bond;
• Rd denotes H or A;
• R3 is H;
• R4 is Hal;
• Hal denotes F, Cl, Br or I;
• A is a branched or linear alkyl having 1 to 12 C-atoms, wherein 1 to 7 H-atoms may be replaced by Hal, OR3, CN or N(R3)2 and wherein 1 to 7 non-adjacent CH2-groups may be replaced by O, or S and/or by —CH═CH— or —C≡C— groups, or denote cycloalkyl having 3-7 ring C atoms;
• n is 4;
• and pharmaceutically acceptable solvates, tautomers, salts and stereoisomers thereof, including mixtures thereof in all ratios.