US 9,006,180 B2Granted

Methods for treating tourniquet-induced injuries

AssigneesCleveland BioLabs, Inc., The Cleveland Clinic Foundation

InventorsAndrei Gudkov, Robert Fairchild

Life of this patent

Estimating the term…

Abstract

The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin.

Claims13

Dependent claims

A method of treating an injury to a mammal, comprising administering to the mammal a composition comprising flagellin,

wherein the injury is tourniquet-induced injury to a limb of the mammal, and
wherein the flagellin comprises the sequence of SEQ ID NO:
8.

Dependencies are inferred from the claim text.

Facts

Application: 14/088,097Filed 22 Nov 2013 · continuation
Priority: 1 Aug 2008
Published: US 2014/0220037 A17 Aug 2014
Granted: 14 Apr 2015
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

A61K 38/164
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from bacteria
A61K 31/355
3,4-Dihydrobenzopyrans, e.g. chroman, catechin: tocopherols, e.g. vitamin E
A61K 31/661
Phosphorus compounds: phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…

Family

Application61/085,766Us provisional application · filed 1 Aug 2008
PCT/US2009/052493Parent of this continuation · filed 31 Jul 2009
Application13/530,580Parent of this continuation · filed 22 Jun 2012
US 8,324,163 B2Parent of this continuation · filed 4 Dec 2012
US 2014/0220037 A1Pre-grant publication · published 7 Aug 2014
US 8,618,059 B2Parent of this continuation
Application13/056,973Parent of this continuation
US 2011/0135665 A1Published application
US 2013/0004515 A1Published application
US 9,006,180 B2This patent

From the US filing history. Foreign family members aren’t listed.

Timeline

Citations

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Facts

Application

14/088,097Filed 22 Nov 2013 · continuation

Priority

1 Aug 2008

Published

US 2014/0220037 A17 Aug 2014

Granted

14 Apr 2015

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

A61K 38/164
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from bacteria
A61K 31/355
3,4-Dihydrobenzopyrans, e.g. chroman, catechin: tocopherols, e.g. vitamin E
A61K 31/661
Phosphorus compounds: phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…

Family

Application61/085,766Us provisional application · filed 1 Aug 2008

PCT/US2009/052493Parent of this continuation · filed 31 Jul 2009

Application13/530,580Parent of this continuation · filed 22 Jun 2012

US 8,324,163 B2Parent of this continuation · filed 4 Dec 2012

US 2014/0220037 A1Pre-grant publication · published 7 Aug 2014

US 8,618,059 B2Parent of this continuation

Application13/056,973Parent of this continuation

US 2011/0135665 A1Published application

US 2013/0004515 A1Published application

US 9,006,180 B2This patent

From the US filing history. Foreign family members aren’t listed.