Methods for treatment of inflammatory diseases
AssigneeThe Feinstein Institute for Medical Research
InventorsKevin Tracey, Sangeeta Chavan
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Abstract
The present invention provides methods of treating inflammatory diseases in a subject comprising administering to the subject a therapeutically effective amount of an agent that inhibits pigment epithelium-derived factor (PEDF) and methods of screening for agents that inhibit PEDF.
Claims9
A method of treating a disease or disorder in a subject, the method comprising administering to the subject a therapeutically effective amount of an antibody that binds to and inhibits pigment epithelium-derived factor (PEDF), wherein the disease or disorder is selected from the group consisting of endotoxemia, sepsis, septicemia, and endotoxic shock.
Dependencies are inferred from the claim text.