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US 9,000,135 B2Granted
Self-reactive arms and prodrugs comprising same
AssigneesCentre Nationale De Recherche Scientifique, Universite De Poitiers
InventorsSebastien Papot, Mickael Thomas
Life of this patent
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Abstract
The present invention relates to a compound of general formula (I): in which: X is OH, NH2, NHOH or RNH, where R may be a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, Y is H, or an electron-withdrawing group, in particular selected from NO2, CF3 or a halogen, R1 and R2 are H or a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, F is a reactive functional group that can be activated by click chemistry.
Claims26
A compound having a general formula (I):
- wherein:
- X is OH, NH2, NHOH or R′NH wherein R′ is a linear or branched, saturated or unsaturated, C1 to C10 alkyl radical,
- Y is an electron-withdrawing group,
- R1 and R2, independently of one another, are H or a linear or branched, saturated or unsaturated, C1 to C10 alkyl radical,
- F is a reactive function group activable by click chemistry.
2 more elements
Dependencies are inferred from the claim text.