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US 8,999,297 B2Granted
Hemostatic agent
AssigneeInter-Med, Inc.
InventorsGary J. Pond, John Baeten
Life of this patent
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Abstract
A generally non-acidic hemostatic agent, having a relatively neutral pH comprising a magnesium compound, such as a magnesium chloride, a magnesium sulfate and/or a magnesium acetate based compound. The resultant agent is generally less caustic than previous agents, when using a similar amount of active material.
Claims20
An aqueous dental hemostatic agent comprising:
- at least one water-soluble magnesium salt selected from the group consisting of magnesium chloride, magnesium sulfate, magnesium acetate, magnesium citrate and combinations thereof, said at least one magnesium salt at between 40-60 weight percent of the agent;
- an acidic compound;
- a pH balancing compound between 2-15 weight percent of the agent;
- and
- KELTROL® T-630 xanthan gum at between 0.5-10.0 weight percent of the agent,
- said agent having a pH value between about 3.0-8.0.
3 more elements
An aqueous, clear dental hemostatic agent comprising:
- a first water-soluble magnesium compound comprising between 1.0-50.0 weight percent of the agent, and a second water-soluble magnesium compound comprising between 0.5-40.0 weight percent of the agent, the first and second water-soluble magnesium compounds selected from the group consisting of magnesium chloride, magnesium sulfate, magnesium acetate, and magnesium citrate, the combination of said first and second water-soluble magnesium compounds comprising between 40.0-60.0 weight percent of the agent;
- a first acidic compound;
- and
- a xanthan gum comprising between 0.5-10.0 weight percent,
- said agent having a pH value between about 3.0-8.0;
- wherein said dental hemostatic agent is a uniform composition with no suspended solids.
3 more elements
A hemostatic agent obtained in a process comprising the steps of:
- (a) dissolving at least one magnesium salt in a volume of water;
- (b) combining at least one acidic compound with the mixture of step (a);
- (c) adding a pH balancing compound to the mixture of step (b) and agitating to provide a clear solution;
- (d) adding a polyol to the clear solution of step (c);
- (e) adding KELTROL® T-630 xanthan gum to the mixture of step (d);
- (f) agitating the mixture of step (e) to completely hydrate the xanthan gum, thereby forming a uniform clear gel with no suspended solids and a pH between about 3.0 and about 8.0, the uniform gel comprising:
- about 40 weight percent to about 60 weight percent of the at least one magnesium salt;
- about 0.1 weight percent to about 20 weight percent of the at least one acidic compound;
- about 1 weight percent to about 20 weight percent of a sweetener;
- up to about 20 weight percent of the pH balancing compound;
- about 5 weight percent to about 25 weight percent of the polyol;
- and
- about 0.5 weight percent to about 10.0 weight percent of the xanthan gum.
10 more elements
Dependencies are inferred from the claim text.