Back to results
US 8,921,419 B2Granted
Triterpenoids and compositions containing the same
AssigneeTrustees of Dartmouth College
InventorsGordon W. Gribble, Liangfeng Fu, Michael B. Sporn, Karen T. Liby
Life of this patent
Estimating the term…
Abstract
The present invention provides triterpenoids produced from natural compounds such as oleanolic acid, ursolic acid, betulinic acid, and hederagenin.
Claims2
A triterpenoid compound of the structure of Formula X, Formula XI, Formula XII or Formula XIII:
- R11 and R12 are each independently hydrogen, hydroxyl, halo, alkyl, alkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, acyl, alkoxy, aryloxy, aralkoxy, heteroaryloxy, hetero-aralkoxy, acyloxy, alkylamino, dialkylamino, arylamino, aralkylamino, heteroarylamino, heteroaralkylamino, amido, or a substituted version of any of these groups, or
- R11 and R12 are taken together and are alkanediyl, alkenediyl, arenediyl, alkoxydiyl, alkenyloxydiyl, alkylaminodiyl, alkenylaminodiyl, or alkenylaminooxydiyl;
- X is ═O or —OMe;
- dashed bonds are present or absent;
- R26 and R27 are independently a hydrogen, halo, alkylthiyl, or substituted or unsubstituted alkylsulfonyl or alkylsulfonyl-O—;
- and
- R28 and R29 are independently —H, or together are ═O.
4 more elements
Dependencies are inferred from the claim text.