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US 8,876,684 B1Granted
Dosimetrically customizable brachytherapy carriers and methods thereof in the treatment of tumors
AssigneeGammaTile LLC
InventorsPeter Nakaji, David Brachman, Heyoung McBride, Emad Youssef, Theresa Thomas
Life of this patent
Estimating the term…
Abstract
Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors.
Claims18
A treatment apparatus comprising:
- a plurality of substantially rectangular flap portions;
- a plurality of petal portions each having
- a first end at least partially coupled to one or more of the plurality of flap portions, and
- a second substantially rounded end opposite the first end;
- and
- a radioactive seed embedded in each of the petal portions;
- wherein the petal portions are positioned in an offset arrangement with reference to the flap portions such that, at a proximal end of the treatment apparatus, a first of the plurality of flap portions extends beyond a first of the plurality of petal portions nearest the proximal end of the treatment apparatus and, at a distal end of the treatment apparatus, a second of the plurality of petal portions extends beyond a second of the plurality of flap portions nearest the distal end of the treatment apparatus;
- wherein the treatment apparatus is substantially flexible and is configured for flexing such that the first flap portion at the proximal end of the treatment apparatus is adjacent to the second petal portion at the distal end of the treatment apparatus such that a treatment surface is exposed on an outer cylindrical surface formed by the flexed treatment apparatus, the treatment apparatus configured for at least partial placement in a cavity of a mammal to apply radioactive energy from the seeds to at least some mammalian tissue forming the cavity.
5 more elements
A treatment apparatus comprising:
- a first plurality of substantially semi-hemispherical petal portions;
- a second plurality of substantially semi-hemispherical petal portions, wherein the first petal portions are coupled to the second petal portions, the first petal portions positioned in an offset arrangement with reference to the second petal portions such that, at a proximal end of the treatment apparatus, a first of the first plurality of petal portions extends beyond a first of the second plurality of petal portions nearest the proximal end of the treatment apparatus and, at a distal end of the treatment apparatus, a second of the second plurality of petal portions extends beyond a second of the first plurality of petal portions nearest the distal end of the treatment apparatus;
- and
- a radioactive seed embedded in each of the first plurality of petal portions;
- wherein the treatment apparatus is substantially flexible and is configured for flexing such that the first petal portion of the first plurality of petal portions at the proximal end of the treatment apparatus is adjacent to the second petal portion of the second plurality of petal portions at the distal end of the treatment apparatus such that treatment surfaces of the first and second plurality of petal portions are exposed on an outer surface formed by the flexed treatment apparatus, the treatment apparatus configured for at least partial placement in a cavity of a mammal to apply radioactive energy from the seeds to at least some mammalian tissue forming the cavity.
2 more elements
A treatment apparatus comprising:
- a plurality of substantially rectangular flap portions;
- a plurality of petal portions each having
- a first end at least partially coupled to one or more of the plurality of flap portions, and
- a second substantially rounded end opposite the first end;
- and
- a radioactive seed embedded in each of the petal portions;
- wherein the treatment apparatus is substantially flexible and is configured for flexing such that a first flap portion at a proximal end of the treatment apparatus is adjacent to a second flap portion at a distal end of the treatment apparatus and a first petal portion at the proximal end of the treatment apparatus is adjacent to a second petal portion at the distal end of the treatment apparatus, such that a treatment surface is exposed on an outer cylindrical surface formed by the flexed treatment apparatus, the treatment apparatus configured for at least partial placement in a cavity of a mammal to apply radioactive energy from the seeds to at least some mammalian tissue forming the cavity.
4 more elements
Dependencies are inferred from the claim text.