N-time-gate data-type for TPSF-based optical imaging
AssigneePresident and Fellows of Harvard College
InventorDavid Jonathan Hall
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Abstract
There is provided a method and system for optical imaging of a light scattering object. The method comprises the detection of one or more time-gates of a temporal point spread function (TPSF) to be used to construct an image of optical properties of the object. The method also comprises the simultaneous detection of two or more selected time-gates using a time-gated camera. The method enables more efficient spatial-temporal acquisition of optical signals for imaging purposes.
Claims24
A method for optical imaging of a light scattering object, the method comprising steps of:
- i) selecting a plurality of time-gates for imaging the object;
- ii) injecting a pulse of light at an injection port into said object at time t;
- iii) collecting light from said object at a plurality of collection ports at the selected plurality of time-gates to provide a plurality of optical signal based temporal point spread function and collecting light only for selected time gates, and not for a series of consecutive time-gates;
- and
- iv) introducing corresponding temporal delay to each one of the optical signal based temporal point spread functions for obtaining staggered optical based temporal spread point spread functions;
- wherein said light collection of said time-gated signals at said selected plurality of time-gates comprises:
- obtaining at least a first derivative of each temporal point spread function;
- and
- identifying one or more time intervals of each temporal point spread function in which a first derivative is zero at a point in said time interval thereby effecting said collection of said time-gated signals.
A system for optical imaging of a light scattering object the system comprising:
- i) at least one light injection port and
- ii) a light collecting apparatus comprising a plurality of collection ports and providing a plurality of sequential time gated optical signal based temporal point spread functions;
- and said light collecting apparatus collects light at a selected plurality of time-gates and not for a series of consecutive time-gates
- wherein said light collection apparatus collects light from an object at the plurality of collection ports and collects light of said time-gated signals at said selected plurality of times-gates by:
- obtaining at least a first derivative of each temporal point spread function;
- and
- identifying one or more time intervals of each temporal point spread function in which a first derivative is zero at a point in said time interval thereby effecting said collection of said time-gated signals.
Dependencies are inferred from the claim text.