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US 8,785,848 B2Granted
Parallel ion mass and ion mobility analysis
AssigneeExcellims Corporation
InventorsChing Wu, Clinton Alawn Krueger, Anthony Joseph Midey, Mark A. Osgood
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Abstract
The present invention relates to a parallel IMS and MS measurement method where a sample flow is split and delivered to an IMS and a MS in parallel. A parallel acquisition MS/IMS method is used to supplement LC-MS and or MS data by using a synchronized MS/IMS acquisition.
Claims20
A method for identifying components of a sample in mass spectral data comprising:
- a. splitting a sample flow into a mass analyzer and an ion mobility based separator for independent parallel ion mass and ion mobility analysis;
- b. acquiring mass spectral data of the sample using the mass analyzer while synchronously acquiring ion mobility data using the ion mobility based separator;
- c. performing a normalization between corresponding peaks of the mass spectral data and that of the peaks in the ion mobility data;
- and
- d. displaying which ion mobility peaks correspond to the mass spectra peaks.
2 more elements
Dependencies are inferred from the claim text.