Oligome-containing pyrrolidine compounds

A compound comprising a pyrrolidine residue covalently attached via a stable linkage to a water-soluble, non-peptidic oligomer, wherein the compound is encompassed within the formula:

• wherein:
• each L is independently selected from the group consisting of hydrogen, hydroxyl, a C1-6 alkyl radical, a C2-6 alkenyl radical, and a C2-6 alkynyl radical;
• p is a whole number from 1 to 6;
• Y is selected from the group consisting of hydrogen, a C1-6 alkyl radical, a C2-6 alkenyl radical, and a C2-6 alkynyl radical;
• R2 is selected from the group consisting of hydrogen, an alkyl radical, an alkenyl radical, an alkynyl radical, a cycloalkyl radical, and an aryl radical;
• X is a spacer moiety;
• and
• POLY is a water-soluble, non-peptidic oligomer having a molecular weight of below about 1500 Daltons.