Compositions and methods relating to proliferative diseases
AssigneeThe Penn State Research Foundation
InventorsGavin P. Robertson, Chandagalu D. Raghavendragowda, SubbaRao V. Madhunapantula, Omer F. Kuzu, Gajanan S. Inamdar
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Abstract
Anti-cancer compositions and methods are described herein. In particular, compositions including one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described. Methods for treatment of pathological conditions particularly cancer, in a subject using one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described herein.
Claims5
An anti-cancer pharmaceutical composition, comprising:
- liposome encapsulated leelamine, wherein the liposomes comprise L-alpha-phosphatidylcholine and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000 in an 80:20 mol % ratio and wherein the liposomes have a net neutral surface charge at physiological pH.
Dependencies are inferred from the claim text.